Selank / TP-7 Liquid Spray is a pre-dissolved, intranasal-format presentation of the synthetic heptapeptide Selank (Thr-Lys-Pro-Arg-Pro-Gly-Pro), a stabilized analog of the endogenous tetrapeptide tuftsin extended with a C-terminal Pro-Gly-Pro. It corresponds to the same molecular entity catalogued in PubChem as CID 11765600 (CAS 129954-34-3), supplied as a ready-to-use liquid rather than lyophilized powder. Selank is also designated TP-7. Intranasal delivery is the route employed in much of the published Selank research, making the liquid spray the reference format for reproducing many experimental conditions.
In the research literature Selank has been studied as a peptide anxiolytic and nootropic, with reported mechanisms centered on modulation of GABAergic gene expression, monoamine and neurotrophin systems, and tuftsin-derived immunomodulation. It is described as producing anxiolytic-type effects without directly binding GABA receptors. This product is provided exclusively for laboratory research and is not intended for human or animal use.
Thr-Lys-Pro-Arg-Pro-Gly-Pro
Research use only — not for human or animal consumption. Per-batch documentation is provided with the material.
Studies using Selank report rapid changes in the expression of genes involved in GABAergic neurotransmission in rodent frontal cortex, and comparative clinical-research literature describes anxiolytic activity broadly comparable to the benzodiazepine medazepam with additional antiasthenic and mild psychostimulant features. Because intranasal delivery was central to much of this work, the liquid spray format is directly relevant to reproducing published experimental conditions.
These findings arise from in-vitro, animal, and investigational clinical research and describe the compound in research contexts only; they are not evidence of clinical efficacy or safety for general use.
Selank (TP-7) was developed by the Institute of Molecular Genetics of the Russian Academy of Sciences with the Zakusov Research Institute of Pharmacology as a stabilized tuftsin analog. Intranasal administration featured prominently in its characterization, and the liquid spray presentation reflects that established research delivery route.
View compound profile on NIH PubChem →
Cited literature refers to laboratory and preclinical research. Selank / TP-7 Liquid Spray is supplied strictly for research use only and is not intended to diagnose, treat, cure, or prevent any disease.
