NAD+ Liquid Spray is a pre-dissolved, intranasal-format solution of beta-nicotinamide adenine dinucleotide (NAD+), the oxidized dinucleotide coenzyme central to cellular energy metabolism and redox chemistry. The active molecule is identical to vialed NAD+ (molecular formula C21H27N7O14P2, molecular weight 663.43 g/mol, CAS 53-84-9); the spray format simply presents it as a ready-to-use liquid rather than a lyophilized powder. It is a small molecule and carries no amino-acid sequence.
As with all NAD+ material, research focuses on its role cycling between oxidized (NAD+) and reduced (NADH) states as the primary electron carrier of energy metabolism, and its function as a consumed substrate for sirtuins, PARPs, and CD38. The liquid-spray presentation is of specific interest in research exploring alternative delivery formats and dissolution kinetics. Supplied for laboratory research use only.
Research use only — not for human or animal consumption. Per-batch documentation is provided with the material.
Research on NAD+ centers on its indispensable role as an electron carrier in energy metabolism and its function as a consumed cosubstrate for sirtuin, PARP, and CD38 enzymes. Declining tissue NAD+ with age and its restoration in preclinical models have made NAD+ metabolism a prominent longevity-research theme, while liquid and intranasal formats are examined as alternative research-delivery approaches.
Reported effects derive from biochemical, cell-culture, and animal studies; NAD+ biology is context-dependent and not established for human therapeutic use. This material is offered strictly as a research reagent.
NAD+ was first described by Arthur Harden and William Young in 1906 as a heat-stable "cozymase" required for fermentation, with its structure and redox role elucidated over following decades by Otto Warburg, Hans von Euler-Chelpin, and others. Interest since the 2000s has focused on NAD+-consuming enzymes such as sirtuins and PARPs, prompting exploration of varied research-delivery formats including liquid sprays.
View compound profile on NIH PubChem →
Cited literature refers to laboratory and preclinical research. NAD+ Liquid Spray is supplied strictly for research use only and is not intended to diagnose, treat, cure, or prevent any disease.
